Panama City is the thriving, urban metropolis that is the heart and soul of Panama. The largest city in Central America, it is said to rival Miami as being the "Capital City of Latin America." Panama City can be accessed by ship at the nearby cruise ports, Fuerte Amadore and Balboa, or by a boat or train ride from Colon. Situated on the Pacific side of the Panama Canal, the city has benefited from a century of wealth generated by the canal.

South America's most popular cruise port, Cartagena is a must-see stop on any Panama Canal or southern Caribbean cruise. The city is safe and tourist-friendly, and most tourist places will speak English and accept U.S. dollars. Beautiful parks, museums and shops welcome visitors, and beautiful Spanish cathedrals and castles lurk around every corner. For beach lovers, there are plenty of sandy beaches and coral reefs within easy access of the city. And for shopaholics, kiosks and tourist shops dot the inner city.

Ocho Rios offers visitors a number of attractions such as Dunn's River Falls and the Craft Market. The small town that only has about 10,000 inhabitants, is visited every year by just under 400,000 tourists.

The island of Roatan sits above the second-largest coral reef in the world, making it an attractive destination for snorkelers, scuba divers and other ocean enthusiasts eager to get a glimpse of one of nature’s most colorful wonders. Book an excursion to visit the beautiful reef by boat, or simply swim from shore – some of the coral is located just 300 feet from the beach. The white sand beaches and crystal clear water make Roatan perfect for swimming and tanning alike.

The Costa Maya is a beautiful, 100-mile-long coastline on the Yucutan Peninsula characterized by white sand beaches and beautiful blue water. Right on the port you can find shopping areas, restaurants and bars, and jet skis for rent, and the nearby city of Mahahual holds a popular, easy to access beach. For those looking for a more private piece of paradise, the more secluded beaches are just a short taxi ride away. One must-see for any visitor of Costa Maya is the Chacchoben Ruins, the remainders of an ancient Mayan city more than a thousand years old. For the best experience, take a guided tour to learn about what life was like for the Mayans – back then and now.