Panama City is the thriving, urban metropolis that is the heart and soul of Panama. The largest city in Central America, it is said to rival Miami as being the "Capital City of Latin America." Panama City can be accessed by ship at the nearby cruise ports, Fuerte Amadore and Balboa, or by a boat or train ride from Colon. Situated on the Pacific side of the Panama Canal, the city has benefited from a century of wealth generated by the canal.

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Port of Spain is the capital of Trinidad and Tobago and the most important port in the country. The city has plenty of attractions from the past centuries. Fort San Andreas was built in 1785 to protect the harbor and visit one of the Gothic Revival style churches or one of the large mosques with minarets. In the Botanical Garden of the city and the zoo, you get insight into the flora and fauna of Trinidad and Tobago.

Macapa is located in the north of Brazil and at the mouth of the Amazon. It is the capital of Amapa and has about 345,000 residents. Macapa is known for its football stadium, whose center line coincides exactly with the equator.

Santarém is located between two rivers, the Amazon and the Rio Tapajós. Santarém area is as diverse as they come! On one part of the city is the noisy jungle where howler monkeys and parrots concert, the beach in the nearby Alter do Chao on the other hand is a place of rest and relaxation.

Boca da Valeria is a traditional river village with 75 inhabitants. Here you can experience traditional Brazilian life and customs and meet the people in traditional dress. The jungle site and the largest freshwater reservoir on Earth are particularly fascinating.

Manaus is the capital of the Brazilian state of Amazonia, and is situated on the Rio Negro, a few kilometers from the mouth of the Amazon. It is possible to find a variety of monkeys and birds in the surrounding jungle. Furthermore, Manaus offers sights of interesting buildings from the rubber boom period.