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Panama City Cruises

Cruise to Panama City with Cruise1st and enjoy unparalleled luxury, top-notch amenities, and exclusive deals. Book your dream cruise today!

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All Inclusive South & Central America, Mexico and USA

All Inclusive South & Central America, Mexico and USA

24 nights

From Miami to Seattle

Norwegian Encore

10/04/2026 - 04/05/2026

Cruise

Flight

Hotel

Inside

from £3,699 pp

Outside

from £4,499 pp

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All Inclusive Machu Picchu, Lake Titicaca & Luxury South America Cruising

23 nights

From Miami to Callao (Lima)

Norwegian Jade

26/02/2026 - 21/03/2026

Cruise

Flight

Train

Hotel

Tour

Inside

from £5,199 pp

Outside

from £5,599 pp

All Inclusive South & Central America and Mexico

19 nights

From Callao (Lima) to San Diego

Norwegian Jade

10/03/2026 - 29/03/2026

Cruise

Flight

Hotel

Inside

from £3,399 pp

Outside

from £3,899 pp

Luxury Central America Tapestry (Miami to Lima) with Miami Stay

17 nights

From Miami to Callao (Lima)

Azamara Onward

04/01/2026 - 21/01/2026

Cruise

Flight

Hotel

All Inclusive

Drinks

Tips

Inside

from £5,799 pp

Outside

from £6,499 pp

Central America from San Diego, California with the Norwegian Jade

Central America from San Diego, California with the Norwegian Jade

15 nights

From San Diego to Miami

Norwegian Jade

12/02/2026 - 27/02/2026

Cruise

Inside

from £2,070 pp

Outside

from £2,445 pp

South America from San Antonio, Chile with the Azamara Journey

19 nights

From San Antonio to Miami

Azamara Journey

10/03/2027 - 29/03/2027

Cruise

All Inclusive

Drinks

Tips

Inside

from £4,227 pp

£4,449

Outside

from £4,702 pp

£4,949

South America from Miami, Florida with the Azamara Onward

15 nights

From Miami to Callao (Lima)

Azamara Onward

06/01/2026 - 21/01/2026

Cruise

All Inclusive

Drinks

Tips

Inside

from £4,284 pp

£4,981

Outside

from £4,759 pp

£5,599

Central America Tapestry Luxury Cruise Followed by a Machu Picchu & Sacred Valley Tour

22 nights

From Miami to Callao (Lima)

Azamara Onward

05/01/2026 - 27/01/2026

Cruise

Flight

Hotel

Tour

All Inclusive

Drinks

Tips

Inside

from £7,499 pp

Outside

from £8,099 pp

South America from San Antonio, Chile with the Azamara Quest

13 nights

From San Antonio to Panama City

Azamara Quest

02/03/2026 - 15/03/2026

Cruise

All Inclusive

Drinks

Tips

Inside

from £3,467 pp

£4,445

Outside

from £3,809 pp

£4,822

South America from Miami, Florida with the Norwegian Jade

12 nights

From Miami to Callao (Lima)

Norwegian Jade

27/02/2026 - 11/03/2026

Cruise

Inside

from £2,595 pp

Outside

from £3,595 pp

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