Named after the Mayaimi tribe that inhabited the area in the 1600s, Miami has skyrocketed to international recognition as the cruise capital of the world. Nestled between Biscayne National Park and Everglades National Park, the incredibly diverse tropical metropolis is equally acclaimed for its stunning sandy beaches, extravagant party scene, street art, natural beauty and glittering skyline. Vibrant, classy, edgy, exciting – Miami is everything you want in a cruise destination and more.

South America's most popular cruise port, Cartagena is a must-see stop on any Panama Canal or southern Caribbean cruise. The city is safe and tourist-friendly, and most tourist places will speak English and accept U.S. dollars. Beautiful parks, museums and shops welcome visitors, and beautiful Spanish cathedrals and castles lurk around every corner. For beach lovers, there are plenty of sandy beaches and coral reefs within easy access of the city. And for shopaholics, kiosks and tourist shops dot the inner city.

Located on the Pacific side of the Panama Canal, Colon is home to a gleaming, modern, tourist-friendly port. Passengers will find plenty of opportunities to shop and eat near the cruise terminals, or to take a shore excursion to see some more scenic parts of Panama. Before the completion of the Panama Canal, the overland rail route played an important role in transporting goods between the Pacific and Atlantic oceans. Passengers today can still take a historic train ride on the Isthmian Railway from Colon to Panama City.

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Puerto Quetzal is an industrial harbor city and home to Guatemala’s largest and most important shipping port. Directly on the harbor, you will find a small tourist area with restaurants, bars and shops. For those looking for a relaxing day, you don’t have to travel far to find a hammock on the beach. More adventurous travelers may want to travel to the nearby city of Antigua, a charming, Spanish city, and nature lovers won’t want to miss the sparkling waters of Lake Atitlan.